In the late 1960s, Hans Laven demonstrated a strategy of population suppression via repeated releases of Wolbachia-infected male mosquitoes.  In general, the strategy was similar to traditional, irradiation-based SIT.  However, the released males carried a Wolbachia infection that is bidirectionally incompatible with the targeted mosquito population.  Over the 12-week period of the study, the strategy was demonstrated to eliminate a field population of medically important mosquitoes.
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