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Characterization of naturally infected and artificially infected insects
Characterization of the sub-cellular interaction between Wolbachia and host cells
Developing applied strategies that employ Wolbachia to modify important insect pests and disease vectors
Wolbachia Transfection
What impact do Wolbachia infections have on host insect survivorship and fitness (longevity, mobility, fecundity, etc...) ?
How is Wolbachia sustained within an insect host population (e.g., what is the maternal inheritance rate? how does Wolbachia affect host reproduction? )
What are the host population level effects of Wolbachia invasion?
What are the mechanisms by which Wolbachia affects host reproduction?
How do Wolbachia infections persist within host cells, while other bacterial infections are eliminated by the immune system?
Do bacteriophages impact Wolbachia? If so, how?
Generating artificial Wolbachia infection types for use in addressing the above questions.
How might Wolbachia infections be used to control important agricultural pests and disease vectors?
Below are some of the questions that we address through research